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If you're getting nothing but a white screen then it is possible that an error is occurring rendering some Aikau content - this maybe something in the header bar for example. Because of the way in which Aikau programmatically constructs the DOM when a page is rendered, it sets the opacity of the entire page to 0 whilst rendering and then resets it to 1 when rendering has completed. This may explain why you're just seeing a white screen - it may also explain why IE (older versions at least that don't support IE are working).
This is just one possibility of course, it could be something entirely different. In browser developer tools I would try setting it to break on exceptions (including caught exceptions) and see if you hit anything ... there are always some caught exceptions in my experience, but it may shed some light on what is happening.
Running in debug mode with logging enabled will probably also help here.